manganeseenhanced magnetic resonance imaging memri

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Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) …

The use of manganese ions (Mn2+) as an MRI contrast agent was introduced over 20 years ago in studies of Mn2+ toxicity in anesthetized rats (1). Manganese-enhanced MRI (MEMRI) evolved in the late nineties when Koretsky and associates pioneered the use of MEMRI …

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Manganese-Enhanced Magnetic Resonance …

Manganese-Enhanced Magnetic Resonance Imaging for Detection of Vasoactive Intestinal Peptide Receptor 2 Agonist Therapy in a Model of Parkinson's Disease …

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Development of a Dendritic Manganese …

Development of a Dendritic Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) Contrast Agent: Synthesis, Toxicity (in Vitro) and Relaxivity (in Vitro, in Vivo) Studies

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Manganese-Enhanced Magnetic Resonance …

Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice. ... In 16-week HIV infected humanized mice, altered MEMRI signal enhancement was observed in affected brain regions including hippocampus, amygdala, thalamus, globus pallidus, ...

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Manganese‐enhanced magnetic resonance …

Manganese‐enhanced magnetic resonance imaging (MEMRI) Koretsky, Alan P.; Silva, Afonso C. 2004-11-01 00:00:00 Alan P. Koretsky* and Afonso C. Silva Laboratory of Functional and Molecular Imaging, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA Received 3 October 2004; Revised 6 October 2004; Accepted 6 October …

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Manganese-Enhanced Magnetic Resonance …

Manganese-Enhanced Magnetic Resonance Imaging for Mapping of Whole Brain Activity Patterns Associated with the Intake of Snack Food in Ad Libitum Fed Rats. Beitrag in einer Fachzeitschrift (Originalarbeit) Details zur Publikation. Autorinnen und Autoren: Hoch T, Kreitz S, Gaffling S, Pischetsrieder M, Heß A. Zeitschrift: → PLoS ONE. Verlag: Public Library of Science. Jahr der ...

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In vivo evaluation of cellular activity in αCaMKII ...

regions. In this study, we performed in vivo manganese-enhanced magnetic resonance imaging (MEMRI) to assess the regional cellular activity in the brains of αCaMKII HKO mice. The signal intensity of MEMRI 24 h after systemic MnCl2 administration reflects functional increases of Mn2+ influx into neurons and glia via transport mechanisms, such

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New Method of Manganese-Enhanced Magnetic …

New Method of Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) for Rat Brain Research JEONG Keun-Yeong, LEE Chulhyun, CHO Jee-Hyun, KANG Ji-Hyuk, NA Heung-Sik Experimental animals 61(2), 157-164, 2012-04-01

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Manganese-Enhanced Magnetic Resonance …

In this study, we used a shock-tube model of blast TBI to determine whether manganese-enhanced magnetic resonance imaging (MEMRI) can serve as a tool to accurately and quantitatively diagnose mild-to-moderate blast TBI. Mice were subjected to a 30 psig blast and administered a single dose of MnCl 2 intraperitoneally.

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Manganese-Enhanced Magnetic Resonance …

Manganese-Enhanced Magnetic Resonance Imaging in Experimental Spinal Cord Injury: Correlation Between T1-Weighted Changes and Mn 2+ Concentrations Nikolay L. Martirosyan, MD 1 Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and …

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Manganese-enhanced magnetic resonance imaging reveals ...

Manganese-enhanced magnetic resonance imaging reveals increased DOI-induced brain activity in a mouse model of schizophrenia Natalia V. Malkovaa,1, Joseph J. Gallagher a, Collin Z. Yub, Russell E. Jacobs, and Paul H. Patterson aDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125; and bSchool of Pharmacy, University of California,

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In vivo tracking of transplanted mononuclear cells …

In vivo tracking of transplanted mononuclear cells using manganese-enhanced magnetic resonance imaging (MEMRI). By Kenichi Odaka, Ichio Aoki, Junji Moriya, Kaoru Tateno, Hiroyuki Tadokoro, Jeff Kershaw, Tohru Minamino, Toshiaki Irie, Toshimitsu Fukumura, Issei …

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Original Article Topical administration of MnCl for ...

by MEMRI in rabbits. Keywords: Manganese-enhanced magnetic resonance imaging, optic nerve injury, topical administration, MnCl 2 Introduction Previous methods used for nerve tract study rely on methods that require the sace of the animals, preventing the use of these methods for longitudinal studies or their eventual use in humans [1-3].

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Biological applications of manganese-enhanced magnetic ...

The manganese ion (Mn2+) has long been used in biomedical research as an indicator of calcium (Ca2+) influx in conjunction with fluorescent microscopy because it is well established that Mn2+ enters cells through voltage-gated Ca2+ channels. Mn2+ is also paramagnetic, resulting in a shortening of the spin-lattice relaxation time constant, T1, which yields positive contrast enhancement in T1 ...

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Manganese-enhanced magnetic resonance …

Manganese-enhanced magnetic resonance imaging (MEMRI) without compromise of the blood-brain barrier detects hypothalamic neuronal activity in vivo. Research output: Contribution to journal › Article. Yu-Ting Kuo, Amy H Herlihy, Po-Wah So, Jimmy D Bell. Overview; Citation formats; Original language: English: Pages (from-to) 1028-34: Number of pages: 7: Journal: Nmr in Biomedicine: Volume: 19 ...

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Neuronal Activity of the Medulla Oblongata Revealed by ...

Manganese-enhanced magnetic resonance imaging (MEMRI) was performed to detect the Mn2+ signal following intraperitoneal injection of MnCl 2. HCl perfusion and citric acid-induced cough caused Fos expressions in the nucleus of solitary tract (nTS), dorsal motor nucleus of the vagus (DMV), paratrigeminal nucleus (Pa5), and intermediate reticular nucleus (IRt), which was higher than HCl …

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Manganese-enhanced magnetic resonance …

There is growing interest in the use of manganese-enhanced MRI (MEMRI) to detect neuronal activity and architecture in animal models. The MEMRI neuronal activity studies have been generally performed either by stereotactic brain injection or by systemic administration of Mn2+ in conjunction with the disruption of the blood–brain barrier (BBB).

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Mapping of the mouse olfactory system with …

As the power of studying mouse genetics and behavior advances, research tools to examine systems level connectivity in the mouse are critically needed. In this study, we compared statistical mapping of the olfactory system in adult mice using manganese-enhanced MRI (MEMRI) and diffusion tensor imaging (DTI) with probabilistic tractography. The primary goal was to determine whether these ...

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Manganese-enhanced magnetic resonance …

Manganese-enhanced magnetic resonance imaging (MEMRI) without compromise of the blood-brain barrier detects hypothalamic neuronal activity in vivo. NMR …

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Manganese-Enhanced Magnetic Resonance Imaging of the ...

Manganese-enhanced magnetic resonance imaging (MEMRI) offers a novel neuroimaging method in visualizing the activity patterns of neural circuits. MEMRI is using the divalent manganese ion, which has been used as a cellular contrast agent. The present study was conducted to determine the contrast-enhancing effects of manganese ion administered ...

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